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The Characteristics And Effects Of 4 - Aminobutyric Acid
Sep 01, 2017

Physiological function of GABA

According to the present study, we find that the physiological activity of GABA is mainly manifested in the following aspects:

(1) calm the nerves and fight the anxiety. Physicians have shown that GABA is an inhibitory neurotransmitter in the central nervous system and is one of the most important neurotransmitters in brain tissue. Its role is to reduce the neuronal activity of nerve cells, prevent overheating, GABA can bind to anti anxiety brain receptors and activate, then with the addition of some material synergistic effect, prevent the anxiety associated with information indicating the central brain arrived.

(2) lowering blood pressure. GABA can act on the blood vessel movement center of the spinal cord, effectively promote the expansion of the blood vessel and reduce the blood pressure.  According to reports, Astragalus and other traditional Chinese medicine effective step-down components that is GABA.

(3) treatment of disease. In 1997, Okuma Makototaro's study showed that GABA was associated with the formation of certain diseases. Parkinson's patients had lower concentrations of GABA in the spinal cord and GABA levels in spinal fluid in epileptic patients were lower than normal. Studies at the Osaka University School of medicine in Japan show that GABA has a significant improvement in Kupperman syndrome. In addition, the reduction of GABA in nerve tissue is also related to the formation of Huntington, Alzheimer's disease and other neurological disorders.

(4) reduce blood ammonia. Clinical and Japanese researchers also believe that GABA inhibits the decarboxylation of glutamic acid and decreases blood ammonia levels. More glutamic acid and ammonia combine to form urea, excreted in vitro to relieve ammonia toxicity, thereby enhancing liver function. Intake of GABA can increase the activity of glucose phosphatase, make the brain cell activity vigorous, can promote the metabolism of brain tissue and restore the function of brain cells, improve the nervous function.

(5) improve brain vitality. GABA can enter the brain three tricarboxylic acid cycle, promote brain cell metabolism, but also can improve the glucose metabolism of glucose phosphatase activity and increased ACh production, dilation of blood vessels to increase blood flow and reduce blood ammonia, promote brain cell function recovery of cerebral The new supersedes the old..

(6) promote ethanol metabolism. Take alcohol as the object, take GABA, then drink 60ml whiskey, take blood to determine the concentration of alcohol and acetaldehyde in the blood, and find that the concentration of the latter is obviously lower than that of the control group.

(7) other. The latest research shows that GABA also has the functions of preventing skin aging, eliminating body odor, improving lipid metabolism, preventing arteriosclerosis, and effectively reducing weight.





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